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The University of Bío-Bío (UBB) is a public university located in the city of Concepcion in Chile. It is a member of the Chilean Traditional Universities.

The founding of the institution is rooted in the establishment of the State Technical University (UTE) in 1947. The Concepcion campus of this institute later became the early incarnation of the University of Bío-Bío in 1980. The University of Chile's Nuble campus was also in operation at this time, having opened its doors in 1966. This was later to become the Professional Institute of Chillan (IPROCH). The current University of Bio-Bio is the result of a merger between these two institutions.

The university has two primary campuses. The Concepcion campus, a lively and bustling environment, is where the engineering, business, sciences and architecture faculties are housed.

The Chillan campus is located in the city of the same name, close to the Andes mountain range. Smaller than Concepcion, but still offering a lively atmosphere, it is described as an ideal place to immerse oneself into the everyday culture of Chile. The campus here is home to the English, graphic design, education and health and nutrition faculties.

The University of Bío-Bío offers more than undergraduate degrees. It also works with outside organisations to develop projects in science and technology. Demonstrating its dedication to innovation, the university has a Business Incubator, designed to aid new business project start-ups.

The mission of UBB is to be nationally recognised as an autonomous and innovative institution "linked to the sustainable development of the Bío-Bío and Nuble regions", and one that makes a positive contribution "to the knowledge society and the harmonious development of the country".